In a subgroup analysis where the subtypes of EGFR mutations were studied, we found that exon 19 deletion and exon 21 L858R point mutation were the two dominant subtypes of TKIs sensitive EGFR mutations in Chinese patients with NSCLC, comprising 43.4% and 48.1% of all the TKIs sensitive EGFR mutations respectively. Here, EGFR is linked to non-small cell lung carcinoma.