The functional experiments also suggested that Wnt-5a knockdown attenuated the aggressiveness of ovarian carcinoma, including proliferation, anti-apoptosis, migration, and invasion, by modulating phenotype-related molecules such as Akt, PI3K, Bcl-xL, VEGF, p70S6k, and survivin. This evidence concerns the gene BCL2L1 and ovarian carcinoma.