PCa related exosomes from clinical samples in general show the presence of some cancer related proteins such as CD9, CD81, and TSG101, Annexin A2, Fatty Acid Synthase (FASN) and a PCa specific biomarker, FOLH1 (Prostate Specific Membrane Antigen or PSMA) [94,95]. Here, CD81 is linked to posterior cortical atrophy.