We confirmed the relative increase of CDO1 expression in glioblastoma when compared with normal brain using the TCGA database (36), identifying approximately a quartile of glioblastoma to exhibit a significant increaseinCDO1 expression when compared withnormal brain (Supplementary Fig. S7A), which is consistent with our data when comparing these tumors to low-grade glioma. Here, CDO1 is linked to glioblastoma.