To determine the impact of HIV-1 infection on the phenotype of CD7+CD56+CD16+ and CD7+CD56negCD16+ NK cells, KIR, C-type lectin-like receptors, and NCRs were assessed in 16 chronically HIV-1-infected subjects and 8 healthy controls (Figure 3). Here, KIR3DL1 is linked to HIV-1 infection.