ACE and metabolic syndrome: Although, Bienertova-Vasku et al. [31] reported that the ACE I/D polymorphism did not express a prediction role on any of the investigated parameters of BMI, total body fat, total body water, waist circumference, hip circumference, WHR, and total body fat in Czech population, Das et al. [32] found that combined APOE∗4/4 and ACE DD genotypes had significant associations with elevated blood pressure, lipid abnormalities, and metabolic syndrome in adult Asian Indians.