In healthy neurons, Tau proteins are well-known for their involvement in the outgrowth of neural processes, axonal transport, development of neuronal polarity, and maintenance of normal neuron morphology [14–16], whereas many neurodegenerative diseases are characterized by Tau hyperphosphorylation, Tau (mis)localisation in neurons, and, consequently, the development of neurofibrillary tangles [17]. The gene discussed is MAPT; the disease is neurodegenerative disease.