SLC17A6 and interstitial cystitis: More research will be necessary to: (1) assess the role of nerve injury-induced upregulation of VGLUT2 in LSC neurons; (2) explore if its expression is also affected by other types of visceral organs pathological conditions (e.g., ulcerative colitis or interstitial cystitis); and (3) what is the consequence of deleting VGLUT2 on autonomically driven nociceptive mechanisms.