Mir-494 was introduced as an oncogenic microRNA to promote tumorigenesis in hepatocellular carcinoma [74], breast cancer by activating myeloid-derived suppressor cells (MDSCs) [75], and non-small-cell lung cancer (NSCLC) cells by inducing Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) resistance [56]. The gene discussed is TNFSF10; the disease is hepatocellular carcinoma.