Six candidate genes including LMNA, Zinc Finger Homeobox 3 (ZFHX3), Matrix Metallopeptidase 2 (MMP2), Angiopoietin-Like 5 (ANGPTL5), Myosin Heavy Chain 7B (MYH7B) and Potassium voltage-gated channel subfamily H member 6 (KCNH6) have been previously linked to heart disease. This evidence concerns the gene ANGPTL5 and heart disorder.