Bayrakli et al [13], Cheng et al [14], Zhang et al [15] and Wawrocka et al [16] also identified 406.4 kb, 566 kb, 527 kb and 600 kb PAX6 3’ deletions in aniridia patients, which contained four genes DCDC1, DNAJC24, IMMP1L and ELP4. These patients had only aniridia and other ocular abnormalities, which is similar to the phenotype observed in most nonsense mutations patients. Here, ELP4 is linked to isolated aniridia.