MMP14 and Familial prostate cancer: In Figure 1A-a, LNCaP cells, a less invasive human prostate cancer cell line, stably expressing membrane type 1 matrix metalloproteinase (MT1-MMP) fused with a green fluorescent protein (GFP) (MT1-GFP) displayed a scattering growth pattern, indicative of invasive behavior, as compared to GFP control cells that instead formed a cell aggregate within the gel.