TGFB1 and neoplasm: Indeed both of these cytokines have been reported to suppress haematopoiesis and Mφ differentiation [54–62]: (2) Analyses of the serum cytokines pattern in orlistat-administered tumor-bearing hosts, as observed in this study, also showed a decline in the level of TGF-β and IL-10 along with elevation of IFN-γ.