Fourteen SNPs in six genes (KIAA1462; MIM# 6, CUL2; MIM#603135, PRKG1; MIM# 176894, FAS; MIM#134637, SLC16A12; MIM#611910, and SORBS1; MIM#605264) showed association with AD at nominal p<0.05. The gene discussed is PRKG1; the disease is Alzheimer disease.