Additionally, several of the pathways of the enteric Tight Junction of the mucosa were significantly repressed in the early stages of infection, especially NRAS, SPTAN1, PRKCG, PPP2R2A, EPB41, PTEN, CSNK2B, YES1, RHOA, CSNK2A1, MYL5, CGN, CLDN1, CDC42, and AKT3 genes. This evidence concerns the gene SPTAN1 and infection.