On the basis of our histopathological findings of CB1 expression in cases of lymphoma cases (Figure S3), we further investigated CB1 expression in HL cell lines L428, L540, L1236, HDLM2, KM-H2, as well as in the non-Hodgkin lymphomas (B-NHL) derived Karpas 422, BJAB, SUDHL8 and Farage cells using RT-PCR and Western blot analyses (Figure 3A,B). This evidence concerns the gene CNR1 and non-Hodgkin lymphoma.