Previous studies have demonstrated that the overexpression of basic fibroblast growth factor (bFGF) and epithelial growth factor (EGF), and their receptors, epithelial growth factor receptor (EGFR) and bFGF receptor (bFGFR), occurs frequently in high-grade gliomas and glioblastomas (1–3). This evidence concerns the gene FGF2 and glioblastoma.