Following the analysis of the correlation of the rs2910829 and rs918592 loci of the PDE4D gene with cerebral infarction in the Uygur and Han populations in this region, it was identified that the C allele at the rs2910829 locus of the PDE4D gene may be a common allele indicating susceptibility to cerebral infarction. Here, PDE4D is linked to brain infarction.