In order to further understand the human ALR (hALR) concentration of serum and study the association of hALR with various liver diseases, particularly with the different stages of type-B hepatitis, it is necessary to investigate the serum hALR concentration in various types and extents of hepatitis and cirrhosis, and the correlation of hALR and disease in detail. The gene discussed is KMT2C; the disease is liver disorder.