For example, numerous chemokines and chemokine receptors, including CCL2/CCR2 (5), CCL3/CCL4 (6), CCL5 (7), CCR5 (8,9), CCR7/CCR8/CCR9/CCR10 (10), CXCL1 (11), CXCL12/CXCR4 (12) and CX3CL1/CX3CR1 (13,14) are implicated in epilepsy. This evidence concerns the gene CCL2 and epilepsy.