Similarly, in ALS, cytoplasmic inclusions contain copper/zinc (CuZn) superoxide dismutase 1 (SOD1) [7–9], TAR DNA binding protein 43 (TDP-43) [10–13], or fused in sarcoma/translated in liposarcoma (FUS/TLS) [14]. The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.