It also infects the adjacent intestinal epithelium at the basolateral membrane (59) but is not an important cause of gastrointestinal disease in humans Reovirus infection induces intestinal IgA production and IgA protects against infection when administered orally at the same time as the virus or when secreted from subcutaneous tumors (9, 60). The gene discussed is CD79A; the disease is Reoviridae infectious disease.