KRCC1 and hemolytic-uremic syndrome: Moreover, the pro-inflammatory potential of EHEC-Hly [9], its production by the vast majority of EHEC strains associated with HUS [13], [14], and expression of the toxin during infection as demonstrated by the development of anti-EHEC-Hly antibodies in most HUS patients [7] and by increased EHEC-hlyA transcription levels in patients' stools [15] offer additional support of the role of EHEC-Hly in the pathogenesis of human diseases.