We looked for a colocalization with CD2, a glycoprotein that is expressed on T, γδ-T, and natural killer (NK) cells [23], and with CD56, a markers of NK and NKT cells, since the stage of dysplastic aberrant crypt foci, (ACF) [24, 25], referred to also as microadenomas, microscopic lesions considered the earliest events in the multistep process of colorectal carcinogenesis. This evidence concerns the gene CD2 and medical procedure.