FASLG and systemic lupus erythematosus: Furthermore, the frequency of CC genotype of C-844T polymorphism of FASL gene was significantly higher in SLE patients than in healthy controls, and the risk of SLE was 2.8-fold higher in individuals with CC genotype in comparison to TT genotype (OR, 2.8 (95% CI, 1.2 to 6.2); P = 0.01).