Abnormal aggregation of protein is a common theme among neurodegenerative diseases: Aβ peptide in Alzheimer’s Disease (AD), tau protein in AD and other tauopathies such as some forms of frontotemporal dementia (FTD), and α-synuclein in Parkinson’s disease and Lewy Body Disease [1-4]. This evidence concerns the gene MAPT and early-onset autosomal dominant Alzheimer disease.