TP53 and neoplasm: Kaplan-Meier curves for relapse and log-rank test comparisons also showed that tumor size (p=0.001), grade (p=0.022), axillary lymph node involvement (p=0.001), ER and/ or PR expression (p=0.011), HER2 amplification (p=0.014), triple negative phenotype (p=0.036), adjuvant hormonotherapy (p=0.025), p53 nuclear expression (p=0.004) and p65 nuclear expression (p=0.002) were associated with the risk of relapse (Table 1).