Similar to the results for peritoneal macrophages, ex vivo stimulation of splenocytes from C. glabrata-infected mice resulted in significantly lower levels of TNF-α production by Dectin-2−/−-deficient cells upon stimulation with either C. glabrata (Fig. 4B) or C. albicans (Fig. 4C), although dissimilarities were detectable earlier in the course of the infection. Here, TNF is linked to infection.