Since completing the tumor vasculogenesis process involves aligning endothelial cells and forming a three-dimensional network of tubes incorporating a functional microvasculature, it was also evaluated whether CD34+ cultured in Matrigel, in the presence of IL-3, SCF and GM-CSF with or without PT45-CM, could organize into a capillary-like structure. The gene discussed is CSF2; the disease is neoplasm.