TPX2 and neoplasm: The risk of developing distant metastases after radical colectomy was much higher in patients with a TPX2-positive tumor relative to patients with a TPX2-negative tumor (P < 0.001) (TPX2-positive, 40 [36.7%] of 109 patients, mean follow-up 64.5 months [range 58.4-70.6]; TPX2-negative, 8 [10.5%] of 76, 81.2 [77.3-85.1]).