Microdeletion studies by Paulsen et al. [28] using genome wide array analysis showed involvement of 7p12.2 (IKZF1), 9p21.3 (CDKN2A), 9p13.2 (PAX5), 12p13.2 (ETV6), 13q14 (RB1), 19p13.3 (TCF3) in association with hyperdiploid ALL. The gene discussed is TCF3; the disease is acute lymphoblastic leukemia.