FISH pattern in MCF from HP peripheral blood consists of two green and red signals, marking ABL on chromosomes 9 and BCR on chromosomes 22, respectively (Figure S1, panel A) All CML-CP patients with typical t(9;22) translocation displayed one BCR-ABL1 fusion signal at the Ph1 chromosome (22q-), one green signal corresponding to normal BCR at 22q and one red signal corresponding to normal ABL at the 9q (Figure 1B-panel A). This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.