As this functional category has yet to be characterized in DCM, we focused on 7 of these ion channels (SCN2B, KCNJ5, KCNJ8, CLIC2, CLCN3, CACNB2, and CACNA1C) in this study, based on the described relationship of these channels with the contraction process (Table 2). This evidence concerns the gene SCN2B and familial dilated cardiomyopathy.