Figure 2b, c show that CD80 protein levels in ACH and Cir patients were higher than those in ACs, HDs or HCC patients (p < 0.05), that CD86 protein levels in ACH patients were higher than those in ACs, HDs, or HCC or Cir patients, that CD86 protein levels in Cir patients were higher than those in HDs or ACs (p < 0.05), that CD83 protein levels in Cir patients were higher than those in HDs, ACs, or ACH or HCC patients (p < 0.05), and that CD83 protein levels in ACH or HCC patients were also higher than those in HDs or ACs (p < 0.05). The gene discussed is CD86; the disease is achondroplasia.