Comparing IPF and NSIP patients, no increase in diagnostic accuracy was seen for the combination analysis (AUC 0.76; 0.63–0.89) with respect to the 2 markers used singly (p = 0.776 and p = 0.182 for MMP-7 and fcDNA, respectively). This evidence concerns the gene MMP7 and idiopathic pulmonary fibrosis.