NPPB and hydrops fetalis: Furthermore, a subgroup of patients with acute HF related symptoms showed an AUC of 0.80 (95% CI 0.75 to 0.84; p < 0.001) at ROC analyses regarding the relationship between sST2 and 1 year mortality [26], which was higher than the AUC value related to NT-proBNP for the same population (0.76, p < 0.001) [32].