IGF2 and rhabdomyosarcoma: p19Arf and Igf-2 were specifically up-regulated in primary rhabdomyosarcomas and in preneoplastic urethral tissue of BALB-p53Neu male mice in comparison to BALB-NeuT and urethral tissue of wild-type male mice (Figure 1), whereas they were significantly down-regulated in urethral tissue of female mice compared to male mice (Figure 1).