When we explored possible relationships between TGF-β1 and clinical parameters, we observed a statistically significant positive correlation between the percentage of TGF-β+ cells and age at onset (Figure 7A), disease burden (Figure 7B), HD development index (Figure 7C), as well as motor performance score (UHDRS1) (Figure 7D). Here, TGFB1 is linked to Huntington disease.