PFKFB3 and prostate carcinoma: Yun et al. reported that glucose transporter 1 (GLUT1) and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) are important molecules for VEGF expression under glucose deprived-conditions in DU145 cells, a human prostate carcinoma cell line [37].