Animals actively treated with either the allergen mix, FPH, or FPH4 displayed a significantly reduced lung inflammation after pollen aerosol challenge; however, lung inflammation was most strikingly suppressed by FPH4 pre-treatment as determined by significantly reduced lung eosinophilia (Fig. 7a) and significantly suppressed IL-5 levels in BAL fluids (Fig. 7b). This evidence concerns the gene IL5 and medical procedure.