When podocytes, casts, and granules from the urine of children diagnosed with IgA nephropathy were immunofluorescently stained for podocalyxin, the degree of fluorescence directly correlated with the degree of glomerular epithelial injury as noted through renal biopsy histologic examination of the same patients [61]. The gene discussed is PODXL; the disease is IgA glomerulonephritis.