Nephrin, podocin, synaptopodin, podocalyxin, CD2AP, ACTN4 (encodes for α-actinin 4), PTPRO (encodes for GLEPP-1), and WT1 mRNA have been isolated from urine of patients with varying glomerulopathies. The gene discussed is NPHS1; the disease is lipoprotein glomerulopathy.