In glomerulonephritis patients (diagnosed with IgA nephropathy, Henoch-Schönlein purpura nephritis, or lupus nephritis) and patients with a diagnosis of nephrotic syndrome, urinary sedimentary podocalyxin (which PPGS was a constituent) was greater than in healthy controls, and podocalyxin concentration was significantly greater in the urinary sediment of glomerulonephritis patients than that of the nephrotic patients [103]. The gene discussed is PODXL; the disease is IgA glomerulonephritis.