We found c-Met inhibition did not change proliferation rate of co-cultured breast cancer cells, KBr1 and KBr2, which was similar to controls (Additional file, Figure 2C), in contrast significantly halted migration capacity of both KBr1 and KBr2 in co-culture with ASCs (Figure 6A, left graph), which expressed twist1 and snail1 levels similar to controls cells (Figure 6A, right graph). Here, TWIST1 is linked to breast cancer.