Cytoplasmic and nuclear expression of PRMT5 was identified in 5 of 5 lung carcinoma cell lines, including NSCLC (NCI-H1299), ADC (NCI-A549), SQC (NCI-H520), and SCLC (NCI-H69 and NCI-H719, Figure 1d). The gene discussed is PRMT5; the disease is small cell lung carcinoma.