Nevertheless, only sMer levels were significantly higher in the presence of lupus-specific autoantibodies, such as anti-dsDNA (18.86 ± 7.78 ng/ml vs. 14.86 ± 6.65 ng/ml; P = 0.0092) (Figure 4D), anti-Smith (anti-Sm) (20.98 ± 9.40 ng/ml vs. 14.81 ± 6.08 ng/ml; P = 0.0064) (Figure 4E), antiribonucleoprotein (anti-RNP) (20.39 ± 9.52 ng/ml vs. 14.81 ± 6.01 ng/ml; P = 0.0070) (Figure 4F) and anti-Ro/SSA (18.42 ± 7.78 ng/ml vs. 14.40 ± 6.33 ng/ml; P = 0.0041) (Figure 4G). The gene discussed is CALR; the disease is systemic lupus erythematosus.