CLDN10 and metastatic malignant neoplasm in the lymph nodes: As shown in Table 2 the expression of claudin-10 was not correlated with age (P =1.000), sex (P =0.664), histological grade (P = 1.000), expression of Ki 67(P =0.464) but correlated with lymph node metastasis (P < 0.01) and expression of E-cadherin (P < 0.01).