CASP1 and ganglioneuroma: Within the experimental group, the expression level of AIM2 was positively correlated with the level of caspase-1, and the level of caspase-1 was positively correlated with the level of IL-1β, suggesting that this inflammation signal transfer pathway was related to AIM2 levels in HBV-GN and, subsequently, that AIM2 may play an important role in the pathogenesis of HBV-GN.