AIM2 and ganglioneuroma: However, in assessing HBV titers, real-time PCR detected serum HBV-DNA in 24 of 54 tested HBV-GN patients, and we found that the expression of AIM2 was significantly higher in patients with high viral load (HBV-DNA ≥ 1 × 105copies/ml) than in patients with low viral load (HBV-DNA < 1 × 105 copies/ml) (p < 0.05).