Increasing evidence suggests that FOXM1 expression is substantially elevated in most human malignancies, such as glioblastoma, lung cancer, hepatocellular carcinoma (HCC), breast cancer, and pancreatic cancer, and plays a crucial role in tumorigenesis, angiogenesis, invasion, and metastasis [17-23]. This evidence concerns the gene FOXM1 and familial pancreatic carcinoma.