CASP1 and infection: Of note, flagellin recognition via Naip5/Nlrc4/caspase-1 account to infection control in vitro and in vivo (Amer et al., 2006; Molofsky et al., 2006; Ren et al., 2006; Zamboni et al., 2006; Coers et al., 2007; Pereira et al., 2011).