CD44 and skin basal cell carcinoma: αvβ6 was found to be overexpressed in the invasive histologic types of BCC, unlike the low-risk nodular variant.34 Other molecules like β-catenin and CD44 were found to be upregulated in the tumor margins and the surrounding stroma of invasive BCC; thus, it may influence the migration of tumor cells and progression of the disease.5,35