Twenty-six genes and other transcripts were differentially expressed in the stage I comparison (19 increased and 7 decreased in AA tumors, Table S3A), including BUB1 mitotic checkpoint serine/threonine kinase (BUB1; 1.05 log2 fold-change; P = 9.80E-04) which is a potent prognostic factor for human breast cancer [36]. The gene discussed is BUB1; the disease is breast cancer.